Chicken Bubble Biscuit Bake Casserole

The ultimate comfort casserole — creamy, cheesy, and filled with tender chicken and golden, fluffy biscuits baked to perfection.

Introduction

Chicken Bubble Biscuit Bake Casserole is the kind of hearty, homey dish that turns any dinner into a cozy occasion. With creamy sauce, chunks of juicy chicken, melty cheese, and soft golden biscuits bubbling on top, it delivers comfort in every bite. It’s the perfect one-pan meal that’s easy to throw together and guaranteed to please the whole family.

Whether you’re preparing a weeknight dinner, hosting a potluck, or simply craving something warm and filling, this casserole delivers classic comfort with minimal effort — a dish that feels like a warm hug straight from the oven.

Ingredients and Their Roles

2 cups cooked chicken, shredded or diced: The hearty base of the casserole. Rotisserie chicken works wonderfully for convenience and flavor.
1 can (10.5 oz) cream of chicken soup: Adds creamy texture and binds the ingredients together.
½ cup sour cream: Introduces tanginess and extra richness for balance.
1 cup shredded cheddar cheese: Provides melty, savory depth and a golden top layer.
½ cup milk: Thins the sauce for smooth consistency and even baking.
1 can (16 oz) refrigerated biscuits: The “bubble” in the name — these bake into fluffy, golden bites throughout the casserole.
½ teaspoon garlic powder: Adds subtle, savory flavor.
½ teaspoon onion powder: Complements the chicken and creamy sauce for a homestyle taste.
Salt and black pepper, to taste: Brings all the flavors together.
1 tablespoon melted butter (optional): Brushed on top for a golden, flavorful finish.
Chopped parsley (for garnish): Adds color and freshness before serving.

Step-by-Step Instructions

Preheat the oven: Set your oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.
Make the sauce: In a large mixing bowl, whisk together the cream of chicken soup, sour cream, milk, garlic powder, onion powder, salt, and pepper until smooth and well blended.
Add chicken and cheese: Stir in the cooked chicken and half of the shredded cheddar cheese until everything is evenly coated in the creamy sauce.
Cut the biscuits: Open the biscuit can and cut each biscuit into quarters. Gently fold the pieces into the chicken mixture until all are coated.
Transfer to the baking dish: Pour the mixture into your prepared dish and spread it evenly. Sprinkle the remaining cheese on top.
Bake: Place the dish in the oven and bake for 25–30 minutes, or until the biscuits are puffed, golden brown, and cooked through in the center.
Finish and serve: Brush the top with melted butter if desired and sprinkle with chopped parsley. Let rest for about 5 minutes before serving.

Why Everyone Loves This Recipe

This Chicken Bubble Biscuit Bake Casserole is loved for its simplicity and satisfying flavor. It’s creamy inside, golden on top, and effortlessly comforting. The biscuits absorb the savory sauce as they bake, becoming tender in the middle and slightly crisp around the edges. It’s also highly versatile — perfect for adding vegetables, using different cheeses, or swapping in leftover turkey after the holidays.

Pro Tips for the Best Casserole

Use pre-cooked chicken: Rotisserie or leftover chicken saves time and adds extra flavor.
Don’t overmix the biscuits: Fold them in gently to keep their texture light and airy.
Add vegetables: Peas, corn, or diced carrots complement the creamy sauce beautifully.
Cheese options: Try sharp cheddar, Monterey Jack, or Colby Jack for delicious variations.
Make it ahead: Prepare the chicken mixture and refrigerate up to 24 hours in advance. Add biscuits just before baking.

Serving Suggestions

Serve your Chicken Bubble Biscuit Bake Casserole with a fresh green salad or steamed vegetables for a balanced meal. It pairs wonderfully with roasted green beans or a spoonful of cranberry sauce on the side. For a cozy dinner, enjoy it with iced tea or lemonade — simple, satisfying, and full of comfort.

Conclusion

This Chicken Bubble Biscuit Bake Casserole is a foolproof, family-approved favorite that turns simple ingredients into a dish full of comfort and flavor. With its creamy sauce, tender chicken, and golden biscuits in every bite, it’s proof that home-cooked meals don’t have to be complicated — just deliciously good.